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<Journal>
<PublisherName>cancercasereports</PublisherName>
<JournalTitle>Cancer Case Reports</JournalTitle>
<PISSN>S</PISSN>
<EISSN>u</EISSN>
<Volume-Issue>Volume 1; Issue 2</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>(2020)</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>Cancer Research</ArticleType>
<ArticleTitle>Complete Overall Tumor Response to Metronomic Chemotherapy, Anti-Estrogen Tamoxifen, High Dose Vitamin C, and Zoledronic Acid of a Young Adult Woman with Metastatic Bilateral Breast Carcinoma: Case Report and First Statement for Morales-Borges Regimen (MBR)</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1</FirstPage>
<LastPage>8</LastPage>
<AuthorList>
<Author>
<FirstName>Raul H.</FirstName>
<LastName>Morales-Borges</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Nelmarie</FirstName>
<LastName>Álvarez-Rodriguez</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Ana</FirstName>
<LastName>Medero-Falero</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Michael J.</FirstName>
<LastName>González</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
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<DOI/>
<Abstract>Breast cancer (BC) is the most prevalent of all cancers in Puerto Rico (PR) and in young women (60 years of age). They tend to have an aggressive disease course with increased probability of poor overall survival and disease-free survival. Standard treatment involves systemic chemotherapy and/or immunotherapy plus antiestrogen therapy for positive hormone-receptors, but other modalities less commonly used are metronomic chemotherapy (mCHT) and alternative treatment of high dose intravenous vitamin C therapy (HDIVC). The Di Bella’s Method (DBM) has been used for years by his inventor and it’s a combination modality with MLT (melatonin), retinoids, vitamins E, D3, and C with differentiating, cytostatic, antiangiogenic, immunomodulating, factorially synergic effects. We are presenting a case of a young adult female patient with mBC treated successfully with a neoadjuvant integrative combined modality using a similar mechanism of DBM which we named Morales-Borges Regimen (MBR).</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Overall tumor response, Metronomic chemotherapy, Tamoxifen, High dose Vitamin C, Zoledronic acid, Young adult woman, Breast carcinoma, Bone metastases, Liver metastases</Keywords>
<URLs>
<Abstract>https://cancercasereports.com/ubijournal-v1copy/journals/abstract.php?article_id=7699&title=Complete Overall Tumor Response to Metronomic Chemotherapy, Anti-Estrogen Tamoxifen, High Dose Vitamin C, and Zoledronic Acid of a Young Adult Woman with Metastatic Bilateral Breast Carcinoma: Case Report and First Statement for Morales-Borges Regimen (MBR)</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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</References>
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